Posterior Reversible Encephalopathy Syndrome after Pediatric Heart Transplantation

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Posterior reversible encephalopathy syndrome after solid organ transplantation.

BACKGROUND AND PURPOSE Posterior reversible encephalopathy syndrome (PRES) is known to occur after solid organ transplantation (SOT), potentially associated with cyclosporine and tacrolimus. In this study, we assess the frequency and clinical and imaging characteristics of PRES after SOT. MATERIALS AND METHODS We identified 27 patients (13 men and 14 women; age range, 22-72 years) who develop...

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Tacrolimus-associated posterior reversible encephalopathy syndrome after solid organ transplantation.

Tacrolimus (TAC) is an immunosuppressant drug discovered in 1984 by Fujisawa Pharmaceutical Co., Ltd. This drug belongs to the group of calcineurin inhibitors, which has been proven highly effective in preventing acute rejection after transplantation of solid organs. However, neurotoxicity and nephrotoxicity are its major adverse effects. Posterior reversible encephalopathy syndrome (PRES) is t...

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Posterior Reversible Encephalopathy Syndrome After Orthotopic Heart Transplantation: A Case Report

BACKGROUND Calcineurin inhibitor-induced posterior reversible encephalopathy syndrome (PRES) is well described in liver and kidney transplant patients, but there is a paucity of data in heart transplant patients. PRES syndrome in the setting of heart transplantation can occur as early as 5 days following transplantation. CASE REPORT A 32-year-old woman who had recently undergone orthotopic hear...

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Posterior reversible encephalopathy syndrome (PRES) is associated with various clinical manifestations such as headache, blurred vision, confusion and tonic-clonic convulsion. Some of the predisposing factors for PRES include hypertensive encephalopathy, preeclampsia and eclampsia, lupus erythematosus, thrombotic thrombocytopenic purpura and long-term use of immunosuppressive drugs. This condit...

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ژورنال

عنوان ژورنال: The Journal of Heart and Lung Transplantation

سال: 2016

ISSN: 1053-2498

DOI: 10.1016/j.healun.2016.01.1176